|                                                                                                                
IGG2 Subclass Deficiency: A Potential Risk Factor of Recurrent Severe Infection to Be Suspected After Complex Surgery

Author(s): Vionnet Salvo Ana Paula1, Plaza López Aresio1, Walo Delgado Paulette1, Moraru Manuela1, Sánchez Romero Isabel2, Peral Ana3, Carbone Campoverde Javier1*

1Immunology Department. Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
2Microbiology Department. Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
3Intensive Care Unit Department. Hospital
Universitario Puerta de Hierro Majadahonda, Madrid, Spain.

*Corresponding author: Javier Carbone, MD, PhD, Head Immunology Department, Hospital Universitario Puerta de Hierro Majadahonda, Calle Joaquin Rodrigo 2, 28222, Madrid, Spain. Phone: 34911916571; Secretary 34911917566; Fax: 34911916657

Citation: Vionnet Salvo AP, Plaza López A, Walo Delgado P, Moraru M, Sanchez Romero I, Peral A, Carbone Campoverde J (2023) IGG2 Subclass Deficiency: A Potential Risk Factor of Recurrent Severe Infection to Be Suspected After Complex Surgery. Ameri J Clin Immu: AJCI:101. Doi: 10.47378/AJCI/2023/10001.

Abstract
IgG2 subclass deficiency is the most common type of IgG subclass deficiency. Immunological monitoring of components of humoral immunity such as IgG subclasses is not included in the evaluation protocols for hospitalized patients who develop serious infections after complex surgery. We report on a patient with IgG2 subclass deficiency who developed severe recurrent bacterial and viral infections after complicated thoracic surgery.

Keywords: Immune monitoring, IgG2 subclass, Infection, Heart surgery.